个人简介 |
(可包含个人履历、学术任职与荣誉、科研项目、代表性成果等,500字左右,代表性项目和成果不计入总字数) 喻会,女,1991年6月生,2019年毕业于武汉大学,获得博士学位。现为附属襄阳医院科研及对外交流办公室工作人员、湖北省胎儿复杂畸形精准诊断临床研究中心学术骨干、人类疾病斑马鱼模型新药筛选襄阳市重点实验室PI、学校“教学名师工作室”学科带头人之一、硕士生导师。从事纳米医学、环境医学、胚胎发育异常和出生缺陷的分子机制研究。现主持湖北省自然科学基金青年项目1项、湖北省卫健委青年人才项目1项和襄阳市研究与开发计划重点项目1项等近十项科研项目,在研经费约百万。近五年来,发表SCI论文十余篇(其中1篇IF>10分)。 主持或参加的科研项目: 1.湖北省重点研发计划(大健康领域支持地方专项),2022BCE021,不育症非遗传因素通过精子表观遗传改变致子代出生缺陷的机制研究,2022-07至2024-06月,30万元,在研,参与; 2.湖北省自然科学基金创新发展基金联合基金,2022CFD010,环境内分泌干扰物致不孕不育和出生缺陷:跨代效应识别及表观机制研究,2023-01至2024-12,20万元,在研,参与; 3.湖北省卫生健康委员会,青年人才项目,WJ2023Q019,双步辐照与抗原递呈功能化提高纳米药物对骨肉瘤光动力-免疫协同治疗效果的研究,2023-01至2024-12,4万元,在研,主持; 4.湖北省自然科学基金,青年项目,2021CFB126,级联靶向纳米药物用于耐药型乳腺癌的CT/PA双模态成像和化疗-光热协同治疗研究,2021-10至2023-09,8万元,在研,主持; 5.襄阳市医疗卫生领域科技计划项目,重点项目,2021YL22,程序化多重靶向纳米药物用于耐药型乳腺癌的CT/PA双模态成像和化疗-光热协同治疗研究,2021-10至2023-09,2万元,在研,主持; 6.襄阳市第一人民医院博士人才启动金资助计划项目(第一批)&襄阳市第一人民医院科技创新项目,XYY2021D04 & XYY2021Q04,基于CT/PA双模态成像的级联靶向纳米药物通过化疗-光热协同治疗耐药型乳腺癌的研究,2021-10至2023-09,14万元,在研,主持; 7.国家自然科学基金委员会,面上项目,51873163,程序化癌细胞和线粒体双重靶向纳米载体用于提高青蒿素类药物的抗肿瘤性能,2019-01至2022-12,59万元,已结题,参加; 8.国家自然科学基金委员会,面上项目,51673152,具有聚集诱导发光特征的高分子纳米载体用于光动力/声动力治疗研究,2017-01至2020-12,62万元,已结题,参加。 代表性论文: [1] Han Yu#*, Qiaohong Xiao#, Guilin Qi, Feixiang Chen, Biyue Tu, Suo Zhang, Yinping Li, Yun Chen, Hui Yu*, Peng Duan*; A hydrogen bonds-crosslinked hydrogels with self-healing and adhesive properties for hemostatic. Front. Bioeng. Biotechnol., 2022, 10: 855013.(二区,IF=6.064) [2]Hui Yu, Jia-Mi Li, Kai Deng, Wei Zhou, Cai-Xia Wang, Qian Wang, Kun-Heng Li, Hong-Yang Zhao, Shi-Wen Huang*; Tumor acidity activated triphenylphosphonium-based mitochondrial targeting nanocarriers for overcoming drug resistance of cancer therapy. Theranostics, 2019, 9 (23): 7033-7050.(一区,IF=11.600) [3]Kai Deng*,Hui Yu, Jia-Mi Li, Kun-Heng Li, Hong-Yang Zhao, Min Ke, Shi-Wen Huang*;Dual-step irradiation strategy to sequentially destroy singlet oxygen-responsive polymeric micelles and boost photodynamic cancer therapy.Biomaterials, 2021, 275: 120959.(一区,IF=15.304) [4]Na Peng*,Hui Yu, Wenjie Yu, Mian Yang, Hongxiang Chen, Tao Zou, Kai Deng, Shiwen Huang*, Yi Liu*; Sequential-targeting nanocarriers with pH-controlled charge reversal for enhanced mitochondria-located photodynamic-immunotherapy of cancer. Acta Biomaterialia, 2020, 105: 223-238.(一区,IF=10.633) [5] Na Peng*,Hui Yu, Ziyu Wang, Yang Zhang, Kai Deng, Jiami Li, Lilin Lu, Tao Zou, Yi Liu, Shiwen Huang*;Dendrimer-grafted bioreducible polycation/DNA multilayered films with low cytotoxicity and high transfection ability; Materials Science & Engineering C, 2019, 98: 737-745.(二区,IF=8.457) [6]Kai Deng, Bo Wu, Cai-Xia Wang, Qian, Wang,Hui Yu, Jia-Mi Li, Kun-Heng Li, Hong-Yang Zhao, Shi-Wen Huang*;An oxidation-enhanced magnetic resonance imaging probe for visual and specific detection of singlet oxygen generated in photodynamic cancer therapy in vivo. Adv. Healthcare Mater, 2020: 2000533.(二区,IF=11.092) [7]Hui Yu, Wei Zhou, Qian Wang, Kai Deng, Jia-Mi Li, Kun-Heng Li, Ren-Xi Zhuo, Shi-Wen Huang*;Mitochondria-targeting delivery of artemisinin for highly efficient cancer therapy. 2018;5thSymposium on Innovative Polymers for Controlled Delivery.(国际会议论文) [8]Bo Wu#, Shu-Ting Lu#,Hui Yu, Ru-Fang Liao, Huan Li, B.V. Lucie Zafitatsimo, Yu-Shuang Li, Ying Zhang, Xiao-Lei Zhu, Hong-Guang Liu, Hai-Bo Xu*, Shi-Wen Huang*, Zhen Cheng*; Gadolinium-chelate functionalized bismuth nanotheranostic agent for in vivo MRI/CT/PAI imaging-guided photothermal cancer therapy. Biomaterials, 2018, 159: 37-47.(一区,IF=15.304) [9]Qian Wang,Jia-Mi Li,Hui Yu;Kai Deng, Wei Zhou,Cai-Xia Wang, Yang Zhang,Kun-Heng Li, Ren-Xi Zhuo, Shi-Wen Huang*.Fluorinated polymeric micelles to overcome hypoxia and enhance photodynamic cancer therapy.Biomater Science, 2018; 6: 3096-107.(二区,IF = 7.590) [10] Wei Zhou,Hui Yu, Liu-Jie Zhang, Bo Wu, Cai-Xia Wang, Qian Wang, Kai Deng, Ren-Xi Zhuo, Shi-Wen Huang*; Redox-triggered activation of nanocarriers for mitochondria-targeting cancer chemotherapy. Nanoscale, 2017, 9: 17044-17053.(一区,IF=8.307) |